Frontier hotspots and research progress on 3D bioprinting in organ reconstruction
10.3969/j.issn.1674-7445.2022.02.003
- VernacularTitle:生物3D打印在器官再造中的前沿热点和研究进展
- Author:
Wenhua HUANG
1
Author Information
1. National Key Discipline of Human Anatomy, School of Basic Medical Science, Southern Medical University, Guangdong Provincial Key Laboratory of Medical Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou 510515, China
- Publication Type:Research Article
- Keywords:
3D bioprinting;
Organ reconstruction;
Organ Transplantation;
Organ-on-a-chip;
Immune response;
Functional reconstruction;
Bionic structure;
Vascularization
- From:
Organ Transplantation
2022;13(2):161-
- CountryChina
- Language:Chinese
-
Abstract:
3D bioprinting is an advanced manufacturing technology that utilizes biomaterials and bioactive components to manufacture artificial tissues and organs. It has been widely applied in multiple medical fields and possesses outstanding advantages in organ reconstruction. In recent years, 3D bioprinted organs have made an array of groundbreaking achievements. Nevertheless, it is still in the exploratory stage of research and development and still has bottleneck problems, which can not be applied in organ transplantation in vivo. In this article, the application of 3D printing technology in medicine, characteristics of 3D bioprinting technology, research hotspots and difficulties in bionic structure, functional reconstruction and immune response of 3D bioprinted organs, and the latest research progress on 3D bioprinting technology were illustrated, and the application prospect of 3D bioprinting technology in the field of organ reconstruction was elucidated, aiming to provide novel ideas for the research and clinical application of organ reconstruction and artificial organ reconstruction, and promote the development of organ transplantation and individualized medicine.
