Progress of researches on anti-infective properties of epigallocatechin-3-gallate
10.16250/j.32.1374.2021101
- VernacularTitle:表没食子儿茶素没食子酸酯抗感染特性研究进展
- Author:
Wei-qin DU
1
;
Ting XUE
2
Author Information
1. Department of Medical Laboratory, the 11th Clinical Medical College, Shanxi Medical University, Lüliang, Shanxi 033000, China
2. National Health Commission Key Laboratory of Pneumoconiosis, Department of Respiratory and Critical Medicine, the First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China
- Publication Type:Journal Article
- Keywords:
(-)-epigallocatechin-3-O-gallate;
Anti-infective activity;
Pharmacological action
- From:
Chinese Journal of Schistosomiasis Control
2022;34(1):102-108
- CountryChina
- Language:Chinese
-
Abstract:
(-)-epigallocatechin-3-O-gallate (EGCG) is the most abundant polyphenol in green tea, which has shown anti-oxidant, anti-inflammatory, anti-thrombotic, anti-radiation, anti-mutant, anti-cancer and anti-fibrotic actions, and has shown improvements of diabetes, obesity, asthma, cancer, cardiovascular diseases and central nervous system disorders. In addition, EGCG is reported to enhance the human immunity. Recently, EGCG has been found to play a vital role in infectious diseases caused by pathogenic microorganisms, including bacteria, fungi, viruses and parasites. The review summarizes the progress of researches on anti-infective properties of EGCG, so as to elucidate the potential role of EGCG in the prevention and treatment of infectious diseases.