Prevalence of upper respiratory tract infection and distribution of virus subtypes in Beijing Area
10.3969/j.issn.1006-2483.2022.01.028
- VernacularTitle:北京地区上呼吸道感染发生情况及病毒感染亚型分布调查
- Author:
Haiming LI
1
;
Jun LI
2
;
Ting WANG
1
Author Information
1. Department of Respiratory Medicine, Beijing Electric Power Hospital, Fengtai , Beijing 100073 , China
2. Department of Occupational Diseases, Xingcheng Branch of Yanhua Hospital, Fangshan, Beijing 102400 , China
- Publication Type:Journal Article
- Keywords:
Upper respiratory tract infection;
Virus infection subtype;
Epidemiology
- From:
Journal of Public Health and Preventive Medicine
2022;33(1):128-131
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the viral infection subtypes and epidemiological characteristics of upper respiratory tract infection (URTI) in Beijing area in 2020, and to provide references for URTI specific treatment and vaccination. Methods A total of 22 318 patients with URTI in Beijing area from January 2020 to December 2020 were enrolled in the study. Basic demographic information and clinical characteristics of the patients were collected, and their respiratory tract samples were collected. Eight major respiratory viruses (including respiratory syncytial virus, parainfluenza virus, adenovirus, coronavirus, influenza virus, rhinovirus, bocavirus, and metapneumovirus) in the respiratory samples were detected by PCR. The pathogen composition and epidemiological characteristics of URTI were analyzed. Results ① Among the 22 318 cases of URTI, most of them were children under 5 years old and elderly patients over 70 years old, accounting for 25.02% and 19.43%, respectively; ② URTI mainly occurred in spring (35.71%) and winter (37.35%); ③ The total positive rate of respiratory virus was 49.35%, among which 45.42% were infected with single virus, 3.30% were infected with two viruses, and 0.63% were infected with three or more viruses; ④ Respiratory syncytial virus (49.35%) had the highest detection rate, followed by parainfluenza virus (12.98%), rhinovirus (9.48%), influenza virus (8.40%), adenovirus (6.01%), bocavirus (4.43%), coronavirus (3.97%), and metapneumovirus (2.90%); ⑤ The detection rates of respiratory syncytial virus and parainfluenza virus in children aged 0-5 years old and the elderly aged over 71 years old were higher than those in other age groups, while the detection rates of other pathogens of all age groups were similar; ⑥ Among 22,318 URTI patients, 290 cases were complicated with pneumonia, with a complication rate of 1.300%. The complication rate of pneumonia in patients with positive virus pathogens was significantly higher than that in patients with negative virus pathogens (χ2=18.011, P<0.05). The complication rate of pneumonia in patients with mixed infection was significantly higher than that in patients with single virus infection (χ2=884.085, P<0.05). Conclusion Children under 5 years old and the elderly over 70 years old are the high-risk population of URTI, and URTI mainly occurs in spring and winter. Respiratory syncytial virus and parainfluenza virus are the main pathogens leading to URTI, and patients with virus infection and mixed virus infection suffer a higher risk of pneumonia.
