Clinical Course after Intravitreal Bevacizumab Injection in Ischemic Central Retinal Vein Obstruction.
10.3341/jkos.2011.52.10.1202
- Author:
Eun Seok YOO
1
;
Young Ju LEW
;
Moon Jung CHOI
;
Jung Il HAN
;
Soo Jin YOO
;
Dong Won LEE
;
Sung Won CHO
;
Chul Goo KIM
;
Tae Gon LEE
;
Jong Woo KIM
;
Jae Heung LEE
Author Information
1. Myung-Gok Eye Research Institute, Kim's Eye Hospital, Seoul, Korea. yjlew@kimeye.com
- Publication Type:Original Article
- Keywords:
Central retinal vein obstruction;
Intravitreal bevacizumab injection;
Neovacular glaucoma
- MeSH:
Antibodies, Monoclonal, Humanized;
Eye;
Glaucoma, Neovascular;
Humans;
Macular Edema;
Retinal Vein;
Retrospective Studies;
Visual Acuity;
Bevacizumab
- From:Journal of the Korean Ophthalmological Society
2011;52(10):1202-1207
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine the clinical outcome of intravitreal bevacizumab injection in patients with ischemic central retinal vein obstruction (CRVO). METHODS: The present study was conducted retrospectively on 56 eyes of 56 patients who were diagnosed with CRVO and classified according to ischemic and non-ischemic type and underwent an intravitreal bevacizumab injection. The present study measured changes in visual acuity and central macular thickness, neovascularization in the anterior segment, development of neovascular glaucoma and other clinical complications. RESULTS: The average number of bevacizumab injections in both groups was 2.07 and 1.62 in the ischemic type. No patients developed neovascular glaucoma in the non-ischemic type group, 14 of 26 eyes in the ischemic type group developed neovascular glaucoma and the mean time to diagnosis was 28.75 weeks. log MAR visual acuity of the ischemic type group prior to injection was 1.56 +/- 0.65 on average which improved to 1.44 +/- 0.97 (p = 0.45). CONCLUSIONS: Intravitreal bevacizumab injection improves the condition of cystic macular edema clinically, but does not affect the development of neovascular glaucoma and improvement of visual acuity in ischemic type CRVO.
