Research advances in the molecular diagnosis of spontaneous bacterial peritonitis
10.3969/j.issn.1001-5256.2022.01.042
- VernacularTitle:自发性细菌性腹膜炎的分子诊断研究进展
- Author:
Haoxin WU
1
;
Zhongjie HU
1
Author Information
1. First Department of Liver Disease Center, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Reviews
- Keywords:
Peritonitis;
DNA, Bacterial;
Diagnosis
- From:
Journal of Clinical Hepatology
2022;38(1):233-235
- CountryChina
- Language:Chinese
-
Abstract:
Spontaneous bacterial peritonitis (SBP) is the most common type of infection in end-stage liver disease, and the diagnosis and treatment of SBP are facing great difficulties and challenges. In recent years, great achievements have been made in molecular diagnostic techniques, but they have not been widely used in clinical practice. Based on the current status of the diagnosis of SBP, this article reviews the advances in molecular microbiological methods in the diagnosis of SBP. Bacterial qualitative analysis alone cannot clarify the association between bacterial DNA and clinical manifestations, and the combination of bacterial quantitative analysis and bacterial type can more accurately describe the biological characteristics of SBP, which may help with the diagnosis of SBP and its special types and the application of antimicrobial agents.
