Value precision quantification of autoantibody assay
10.3760/cma.j.cn114452-20210719-00441
- VernacularTitle:重视自身抗体的精准定量检测
- Author:
Xiaoqi CHEN
1
;
Jianjun CAI
;
Yirong LI
Author Information
1. 武汉大学中南医院风湿免疫科，武汉430071
- Keywords:
Autoantibody;
Precision;
Quantification
- From:
Chinese Journal of Laboratory Medicine
2021;44(11):987-990
- CountryChina
- Language:Chinese
-
Abstract:
Autoantibodies play an important role in aiding to the diagnosis, as well as judging diseases activity and monitoring treatment of autoimmune disorders. The combined detection of multiple autoantibodies is the current mainstream detection method. However, results are frequently reported as qualitative or semi-quantitative. The newly released diagnostic/classification standards for autoimmune diseases require quantitative detection data about the level of autoantibodies. The higher the level of autoantibodies is, the more likely the patient is to be diagnosed as an autoimmune disease, and it may be more relevant to the activity of the autoimmune disease. This article makes an introduction about the clinical value of accurate quantitative detection of autoantibodies as well as the current statues and challenges at the moment.
