Advances in the clinical application of optical coherence tomography angiography in glaucoma
10.3760/cma.j.cn511434-20210316-00142
- VernacularTitle:光相干断层扫描血管成像在青光眼诊断随访中的应用研究进展
- Author:
Jiazhi LI
1
;
Li TANG
;
Jingqi AN
Author Information
1. 四川大学华西医院眼科，成都 610041
- Keywords:
Glaucoma;
Tomography, optical coherence;
Regional blood flow;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2021;37(6):479-482
- CountryChina
- Language:Chinese
-
Abstract:
As a neurodegenerative disease of the retina, glaucoma can cause irreversible vision loss in patients. More and more evidences indicate that systemic blood flow abnormalities, decreased optic nerve blood flow, and retinal microcirculation disorders are related to the mechanism of glaucoma ganglion injury. Optical coherence tomography (OCTA) has the advantages of non-invasive, high resolution, quick inspection, three-dimensional imaging, and quantitative blood flow perfusion. Compared with other blood flow detection methods such as color ultrasound Doppler, laser speckle blood flow imaging, etc. it has higher performance and accuracy, and is easier to be applied in clinical practice. OCTA can not only be used for the early diagnosis and follow-up of glaucoma, but has a strong correlation with retinal nerve fiber layer thickness and visual field parameters; it can also provide objective data for the follow-up of patients with advanced glaucoma to assess the progress of the disease. In the future, OCTA is expected to become a routine detection method and follow-up method for the diagnosis of glaucoma.
