Relationship between preoperative frailty and postoperative cognitive dysfunction in elderly patients undergoing non-cardiac surgery
10.3760/cma.j.cn131073.20210202.00508
- VernacularTitle:非心脏手术老年患者术前衰弱与术后认知功能障碍的关系
- Author:
Zhengwen CHEN
1
;
Yanping WANG
;
Aifang CHEN
;
Ling ZHANG
Author Information
1. 新疆医科大学第二附属医院麻醉科，乌鲁木齐 830002
- Keywords:
Neurasthenia;
Cognitive dysfunction;
Postoperative complications;
Aged
- From:
Chinese Journal of Anesthesiology
2021;41(5):542-545
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship between preoperative frailty and postoperative cognitive dysfunction (POCD) in elderly patients undergoing non-cardiac surgery.Methods:A total of 336 elderly patients of both sexes, aged≥65 yr, of American Society of Anesthesiologists physical status Ⅱ or Ⅲ, with body mass index of 18.6-25.1 kg/m 2, undergoing elective non-cardiac surgery under general anesthesia, were enrolled in the study.Faltering status was assessed with the Clinical Faltering Scale at 1 day before surgery.Mini-Mental State Examination score, Digital Span Test, Digit Symbol Substitution Test, Stroop Color and Word Test, Visual Word Learning Test and Trail Making Test were performed at 1 day before surgery and at 1, 7 and 30 days after surgery.The Z score was used to identify POCD.The patients was divided into non-POCD group and POCD group according to the occurrence of POCD within 30 days after surgery.Logistic regression analysis was used to identify the risk factors for POCD in elderly patients undergoing non-cardiac surgery. Results:The results of logistic regression analysis showed that preoperative frailty and diabetes mellitus were independent risk factors for POCD in elderly patients undergoing non-cardiac surgery ( P<0.05). Conclusion:Preoperative frailty is an independent risk factor for POCD in elderly patients undergoing non-cardiac surgery.
