Research progress of salvage lymph node dissection in advanced prostate cancer

VernacularTitle:挽救性淋巴结清扫术在前列腺癌根治性治疗后淋巴结复发患者中的应用进展
Author: Wei HE ¹ ; Qi ZHANG ; Dahong ZHANG
Author Information

1. 浙江省人民医院泌尿外科　杭州医学院附属人民医院　杭州医学院泌尿外科研究所，杭州　310014
Keywords: Prostatic neoplasms; Salvage lymph node dissection; Biochemical recurrence
From: Chinese Journal of Urology 2021;42(9):717-720
CountryChina
Language:Chinese
Abstract: Prostate cancer (PCa) is one of the most common invasive cancers in men. Radical prostatectomy is the gold standard for localized prostate cancer, but the postoperative biochemical recurrence rate can reach 20%-50%. In some cases, salvage lymph node dissections (SLND) seem to improve cancer control and delay systemic treatment. In this article, we review the current state of diagnostic imaging, accurate patient selection criteria, exploration of SLND surgical procedures, as well as the safety and tumor outcomes of SLND. Overall, although there is still a lack of strong prospective evidence to support the role of SLND, advances in preoperative imaging techniques and the widespread use of minimally invasive surgery have led to encouraging tumor outcomes with SLND. However, further large-scale and high quality trials are needed to confirm the effectiveness and safety of SLND.