Research progress on the effect of high-fat diet on intestinal homeostasis via microbial metabolites
10.3760/cma.j.cn115822-20210310-00055
- VernacularTitle:高脂饮食通过菌群代谢产物对肠道稳态影响的研究进展
- Author:
Jiao JIAO
1
;
Wentian LIU
Author Information
1. 天津医科大学总医院消化科 300052
- Keywords:
High-fat diet;
Microbial metabolites;
Intestinal homeostasis;
Inflammatory bowel disease;
Colorectal cancer
- From:
Chinese Journal of Clinical Nutrition
2021;29(2):114-122
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal homeostasis is affected by many factors such as genetics, environment, and eating habits. High-fat diet, as one of the influencing factors, may affect the intestinal microbial metabolites, destroy the integrity of the intestinal mucosal barrier and induce intestinal immunity dysfunction, which in turn leads to imbalance of intestinal homeostasis and occurrence of digestive diseases. This article reviews the recent research progress on the effects of high-fat diet on intestinal homeostasis via microbial metabolites.
