Clinical significance of abnormal inflammatory markers in Mycoplasma pneumoniae pneumonia
10.3760/cma.j.cn101070-20210725-00879
- VernacularTitle:肺炎支原体肺炎炎症指标异常的临床意义
- Author:
Yingxue ZOU
1
Author Information
1. 天津市儿童医院（天津大学儿童医院）呼吸二科 300074
- Keywords:
Mycoplasma pneumoniae;
Serum biomarkers;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(16):1209-1214
- CountryChina
- Language:Chinese
-
Abstract:
Mycoplasma pneumoniae pneumonia (MPP) is usually self-limited.However, refractory MPP affects some patients even after the treatment of macrolide antibiotics, leading to clinical or imaging deterioration.In recent years, novel insights in the clinical manifestations of MPP have been largely obtained, especially in the unique epidemiological characteristics of mycoplasma pneumoniae (MP) in 3 to 5 years interval, and the relationship between refractory and severe MP infection, outbreak and epidemic.The rapid laboratory diagnosis of MP and the selection of optimal therapeutic strategy for severe MPP cases are the huge challenges in clinical practice.Therefore, many studies have been performed to explore the early warning role of serum biomarkers in severe cases, as well as their diagnostic and therapeutic potentials.However, the understanding of the exact application value of these inflammatory markers is still limited.The ideal blood biomarkers of MPP should be reliable, rapid, and widely used, which can assist the diagnosis of severe cases, determination of complications, understanding of the pathogenesis and predictions of clinical outcomes or treatment effect.
