Gut microbiota and hematological malignancies
10.3760/cma.j.cn371439-20201019-00086
- VernacularTitle:肠道微生物群与血液肿瘤
- Author:
Liya WEI
1
;
Zhi GUO
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院深圳医院血液肿瘤科，深圳 518116
- Keywords:
Microbiota;
Hematological neoplasms;
Therapy;
Microbial translocation;
Blood stream infection
- From:
Journal of International Oncology
2021;48(7):445-448
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, driven by metagenomics sequencing technology, it has been found that compositional changes and diversity changes of gut microbiota are related to the occurrence of hematological malignancies. Gut microbiota affects the development of the hematopoietic system and the risk stratification of hematological malignancies. Microbial translocation plays an important role in and blood stream infection. Gut microbiota imbalance and blood stream infection affect the therapeutic effect of hematological malignancies. Probiotics and fecal microbiota transplant can restore the diversity of gut microbiota.
