Advances in pathogenic mechanism of respiratory syncytial virus
10.3760/cma.j.issn.1673-4408.2021.07.006
- VernacularTitle:呼吸道合胞病毒致病机制的研究进展
- Author:
Ping LIANG
1
;
Hanmin LIU
Author Information
1. 四川大学华西第二医院小儿呼吸免疫科 出生缺陷与相关妇儿疾病教育部重点实验室，成都 610041
- Keywords:
Respiratory syncytial virus;
Pathogenic mechanism;
Immune response;
Drug target
- From:
International Journal of Pediatrics
2021;48(7):459-463
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory syncytial virus is a leading cause of acute lower respiratory infection(ALRI)in infants and young children, remains a significant burden to global health.Unfortunately, no effective treatments or vaccine has been developed.However, in recent years, there has been substantial advance in understanding the pathogenic mechanism of RSV, which is always a research hotspot to seek drug and vaccine targets.This review summarizes the progress in the RSV particles structure, viral protein function and the host immune response, and hopes to describe a clearer understanding of RSV pathogenic mechanism which is essential for developing interventions.
