Analysis of risk factors for surgical treatment of congenital pulmonary venous stenosis combined with congenital heart disease
- VernacularTitle:先天性肺静脉狭窄合并先天性心脏病外科治疗的危险因素分析
- Author:
Xiaodong LV
1
;
Zhan GAO
2
;
Xiao TENG
1
;
Qiang GAO
2
;
Zhongdong HUA
1
;
Jun YAN
1
;
Zewei ZHANG
2
;
Shoujun LI
1
Author Information
1. Pediatric Cardiac Surgery Center, Fuwai Hospital, Beijing Union Medical University, Chinese Academy of Medical Sciences, Beijing, 100037, P.R.China
2. Department of Cardiovascular Surgery, Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, P.R.China
- Publication Type:Journal Article
- Keywords:
Pulmonary vein stenosis;
congenital heart disease;
pulmonary hypertension;
risk factor;
surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(12):1455-1460
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore risk factors associated with mortality and restenosis after the surgery for congenital pulmonary venous stenosis (CPVS) combined with congenital heart disease. Methods From May 2007 to August 2019, 58 patients received surgical relief of CPVS combined with congenital heart disease, including 24 males and 34 females, aged 17.2±26.3 months, weighing 8.8±8.2 kg. Endpoints were death and restenosis, and the risk factors were analyzed. A univariate and multivariate risk analyses were performed. Results Preoperative pulmonary venous stenosis severity score (PVSSS) was 4.5±2.7. Average pulmonary vein counts with CPVS was 1.9±1.0. There were 2 (3.4%) early deaths. The mean follow-up time was 2-145 (49.8±40.0) months. The 1-, 2-, 3- and 5-year overall survival rates were 86.7%, 81.3%, 78.5% and 73.6%, respectively, and the pulmonary venous restenosis-free rates were 79.6%, 68.5%, 68.5% and 68.5%, respectively. Preterm birth was an independent risk factor for mortality. The pulmonary venous peak flow rate ≥ 1.2 m/s at discharge was an independent risk factor for mortality and restenosis. Conclusion The prognosis of CPVS is still poor. Postoperative residual stenosis at discharge is an independent risk factor for death and restenosis.
