Risk factors for early in-hospital death in patients with acute Stanford type A aortic dissection
- VernacularTitle:急性Stanford A型主动脉夹层术后患者院内早期死亡危险因素分析
- Author:
Tianjiang LI
1
;
Mangyuan WANG
1
;
Qiang HUO
1
Author Information
1. Department of Cardiology, Heart Center, The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, P.R.China
- Publication Type:Journal Article
- Keywords:
Acute Stanford type A aortic dissection;
risk factor;
white blood cell count;
bilirubin;
creatinine;
cardiopulmonary bypass time;
surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(12):1447-1454
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for early in-hospital death in patients with acute Stanford type A aortic dissection and emergency surgical treatment. Methods We retrospectively analyzed the clinical data of 189 patients with acute Stanford type A aortic dissection who underwent surgery in the First Affiliated Hospital of Xinjiang Medical University between January 2017 and January 2020. There were 160 males and 29 females with an average age of 46.35±9.17 years. All patients underwent surgical treatment within 24 hours. The patients were divided into a survival group (n=160) and a death group (n=29) according to their outcome (survival or death) during hospitalization in our hospital. Perioperative clinical data were analyzed and compared between the two groups. Results The overall in-hospital mortality was 15.34% (29/189). There was a statistical difference between the two groups in white blood cell count, blood glucose, aspartate aminotransferase (AST), bilirubin, creatinine, operative method, operation time, aortic occlusion time, or cardiopulmonary bypass time (P<0.05). Multivariate regression identified white blood cell count [OR=1.142, 95%CI (1.008, 1.293)], bilirubin [OR=0.906, 95%CI (0.833, 0.985)], creatinine [OR=1.009, 95%CI (1.000, 1.017)], cardiopulmonary bypass time [OR=1.013, 95%CI (1.003, 1.024)] as postoperative risk factors for early in-hospital death in the patients undergoing acute Stanford type A aortic dissection surgery (P<0.05). Conclusion Our study demonstrated that white blood cell, bilirubin, creatinine and cardiopulmonary bypass time are independent risk factors for in-hospital death after acute Stanford type A aortic dissection surgery.
