Metabolism Levels in Precentral Gyrus of Patients after Spinal Cord Injury
10.3969/j.issn.1006-9771.2020.04.003
- VernacularTitle:脊髓损伤患者大脑中央前回的代谢改变
- Author:
Ya-jing LI
1
;
Jian-jun LI
1
;
Feng GAO
1
;
Yun GUO
2
;
Jun LIU
1
;
Pei-pei XU
1
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
2. Beijing Tsinghua Changgeng Hospital, Beijing 102218, China
- Publication Type:Research Article
- Keywords:
spinal cord injury;
magnetic resonance spectroscopy;
precentral gyrus;
primary motor cortex;
gial cells;
hyperplasia;
repair
- From:
Chinese Journal of Rehabilitation Theory and Practice
2020;26(4):382-387
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of metabolite concentration in the precentral gyrus (primary motor cortex, M1) in spinal cord injury (SCI) patients. Methods:From December, 2018 to October, 2019, 20 SCI patients and 15 healthy controls were scaned with magnetic resonance spectroscopy to measure the concentrations of N-acetylaspartate (NAA), choline (Cho), creatine (Cr) and myo-inositol (MI) in region of interest (ROI) of left M1. Results:Concentration of MI was more in the patients than in the controls (t = 3.745, P < 0.01). There was no significant difference in the concentrations of NAA, Cho and Cr, as well as the ratios of NAA/Cr, Cho/Cr, Cho/NAA between the patients and the controls (t < 1.431, P > 0.05). Conclusion:There may be hyperplasia of glial cells in M1 of SCI patients, indicating compensatory repair in cerebral motor cortex.
