Two new pyranonaphthoquinones from Mansoa alliacea.
10.19540/j.cnki.cjcmm.20210317.201
- Author:
Jing LUO
1
;
Zhen-Long WU
1
;
Xiao-Jun HUANG
1
;
Xiao-Qi ZHANG
1
;
Chun-Lin FAN
1
;
Wen-Cai YE
1
;
Ying WANG
1
Author Information
1. Center for Bioactive Natural Molecules and Innovative Drugs Research,College of Pharmacy,Jinan University Guangzhou 510632,China Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine & New Drugs Research,Jinan University Guangzhou 510632,China.
- Publication Type:Journal Article
- Keywords:
Mansoa alliacea;
chemical constituents;
mansonin A;
mansonin B;
pyranonaphthoquinone
- MeSH:
China;
Chromatography, High Pressure Liquid;
Phytochemicals;
Plant Leaves
- From:
China Journal of Chinese Materia Medica
2021;46(13):3364-3367
- CountryChina
- Language:Chinese
-
Abstract:
Mansoa alliacea,commonly known as garlic vine,is native to the tropical rain forests of South America and widely cultivated in South China. As a popular folk medicine with various biological activities,however,this plant remains to be fully elucidated in terms of its phytochemical constituents. In this study,two new pyranonaphthoquinones were isolated from the 95% ethanol extract of the leaves and twigs of M. alliacea by various chromatographic approaches including silica gel,octadecyl silica( ODS),Sephadex LH-20,and preparative high-performance liquid chromatography( PHPLC). Their structures were determined to be 8,9-dimethoxy-α-lapachone( 1) and 7-hydroxy-8,9-dimethoxy-α-lapachone( 2) by comprehensive spectroscopic analyses and therefore respectively named as mansonin A( 1) and mansonin B( 2).
