Value of Contrast-enhanced Ultrasound Parameters in Evaluating K-W Nodule Formation in Diabetic Nephropathy.

Author: Yi-Ru WANG ¹ ; Nan LI ¹ ; Ping ZHAO ¹ ; Lin LIN ¹ ; Xiao-Qi TIAN ¹ ; Zhe-Yi DONG ² ; Jiao-Na LIU ² ; Qian WANG ² ; Qiu-Yang LI ¹ ; Jie TANG ¹ ; Yu-Kun LUO ¹
Author Information

1. Department of Ultrasound, the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China.
2. Department of Nephrology,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China.
Publication Type:Journal Article
Keywords: K-W nodules; contrast-enhanced ultrasound; diabetic nephropathy; microperfusion
MeSH: Contrast Media; Diabetes Mellitus; Diabetic Nephropathies/diagnostic imaging*; Humans; Ultrasonography
From: Acta Academiae Medicinae Sinicae 2021;43(3):314-321
CountryChina
Language:Chinese
Abstract: Objective To discuss the value of contrast-enhanced ultrasound(CEUS)parameters in evaluating the formation of Kimmelstiel-Wilson(K-W)nodules in diabetic nephropathy(DN).Methods Sixty-two patients pathologically diagnosed with DN and undergoing CEUS in the First Medical Center of Chinese PLA General Hospital from March 2017 to January 2020 were assigned into two groups according to whether K-W nodules were formed.The cortical CEUS parameters and the ratios of cortical to medullary CEUS parameters were compared between the two groups.Results The 62 patients included 19 patients without K-W nodules(group A)and 43 patients with K-W nodules(group B).The median rise time(