Follow - up prognostic study on two imported patients with human African trypanosomiasis
10.16250/j.32.1374.2021010
- VernacularTitle:2 例输入性非洲锥虫病的随访预后研究
- Author:
Yuan-Yuan LI
1
;
Xiao-Ling CHEN
2
;
Qing LIU
3
;
Xin-Yu WANG
4
;
Mu-Xin CHEN
5
;
Qin LIU
5
Author Information
1. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China; Co-first authors
2. Fujian Medical University Union Hospital, China; Co-first authors
3. Fujian Medical University Union Hospital, China
4. Huashan Hospital Affiliated to Fudan University, China
5. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai 200025, China
- Publication Type:Journal Article
- Keywords:
Human African trypanosomiasis;
Trypanosoma brucei rhodesiense;
Trypanosoma brucei gambiense;
Prognosis
- From:
Chinese Journal of Schistosomiasis Control
2021;33(3):293-296
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognosis of two rare imported patients with human African trypanosomias (HAT) after treatment in a follow-up study, and to evaluate the therapeutic efficacy, so as to provide insights into the treatment of imported HAT patients. Methods The white blood cells in cerebrospinal fluid samples and the trypomastigotes in cerebrospinal fluid and blood samples were monitored in an imported case with Trypanosoma brucei rhodesiense infection 1, 3, 11 and 25 months post-treatment and in an imported case with T. brucei gambiense infection 1, 3, 8 and 12 months post-treatment to evaluate the therapeutic efficacy and prognosis. Results There were 1, 1, 4 and 2 white blood cells in per μL of cerebrospinal fluid in the case with T. brucei rhodesiense infection 1, 3, 11 and 25 months post-treatment, and there were 3, 6, 4 and 3 white blood cells in per μL of cerebrospinal fluid in the case with T. brucei gambiense infection 1, 3, 8 and 12 months post-treatment. In addition, no trypomastigotes were identified in the cerebrospinal fluid or blood samples of either case with T. brucei rhodesiense or T. brucei gambiense infection. Conclusion Following standardized treatment, two imported cases with human African trypanosomiasis cases recover satisfactorily, without any signs of relapse.
