Type B polycyclic polyprenylated acylphloroglucinols from the roots of Hypericum beanii.
10.1016/S1875-5364(21)60037-7
- Author:
Wei-Xian LI
1
;
Wen-Jun XU
1
;
Jun LUO
1
;
Lei YANG
2
;
Ling-Yi KONG
3
,
4
Author Information
1. Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
2. Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: dorothy19802003@gmail.com.
3. Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: cpu_lykong@
4. com.
- Publication Type:Journal Article
- Keywords:
ECD;
Hyperbeone A;
Hypericum beanii;
Polyprenylated acylphloroglucinol
- From:
Chinese Journal of Natural Medicines (English Ed.)
2021;19(5):385-390
- CountryChina
- Language:English
-
Abstract:
Two new type B polycyclic polyprenylated acylphloroglucinols (PPAPs) (1 and 2) and a known biogenetic precursor hyperbeanol Q (3) were isolated from the root extract of Hypericum beanii, a medicinal plant widespread in southwest China. Their chemical structures were elucidated by 1D/2D NMR and HRESIMS data analysis, and absolute configurations were determined through detailed electric circular dichroism (ECD) analysis including ECD exciton chirality, Mo
