Prognostic Value of Interim
10.19746/j.cnki.issn.1009-2137.2021.03.013
- Author:
Tai-Song WANG
1
;
Wen-Li QIAO
1
;
Yan XING
1
;
Jin-Hua ZHAO
2
,
3
Author Information
1. Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
2. Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China,E-mail: zhaojinhua1963@
3. com.
- Publication Type:Journal Article
- MeSH:
China;
Disease-Free Survival;
Fluorodeoxyglucose F18;
Humans;
Lymphoma, Extranodal NK-T-Cell/diagnostic imaging*;
Positron Emission Tomography Computed Tomography;
Prognosis;
Retrospective Studies
- From:
Journal of Experimental Hematology
2021;29(3):731-734
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the value of interim
METHODS:Twenty-one patients with ENKTL who were pathologically diagnosed at Shanghai General Hospital of Nanjing Medical University (Shanghai General Hospital) from January 2015 to December 2018 were retrospectively collected, and
RESULTS:After treatment, 11 patients had complete remission (CR), 3 had partial remission (PR), 1 had stable disease (SD), and 6 had disease progression (PD). The CR patients' △SUVmax was significantly higher than non-CR patients ［(66.07±22.33)% vs (36.87±23.28)%, t=2.927, P=0.009］. Calculated from the receiver operating curve (ROC), the optimal cut-off point of ΔSUVmax was 51.45%. The median follow-up time was 32 months. Kaplan-Meier survival analysis showed that KPI, DS and ΔSUVmax had significance in predicting PFS and OS (P<0.05). COX regression analysis showed that DS was an independent risk factor affecting PFS (P<0.05), and KPI and ΔSUVmax were independent risk factors affecting OS (P<0.05).
CONCLUSION:Interim
