Effect of calorie-enriched formula on postoperative catch-up growth in infants with cyanotic congenital heart disease: a propective randomized controlled study.
- Author:
Hong-Mei ZHOU
1
;
Qiu QIU
1
;
Meng-Huan YAN
1
;
Li-Juan PENG
;
Jing-Jing FANG
;
Bing-Jie ZHOU
;
Sha-Sha YANG
;
Gang-Cheng ZHANG
1
Author Information
1. Congenital Heart Disease Center, Wuhan Asia Heart Hospital, Wuhan 430000, China.
- Publication Type:Randomized Controlled Trial
- MeSH:
Body Weight;
Energy Intake;
Heart Defects, Congenital/surgery*;
Humans;
Infant;
Malnutrition;
Nutritional Status;
Prospective Studies
- From:
Chinese Journal of Contemporary Pediatrics
2021;23(1):78-83
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effect of calorie-enriched formula on postoperative catch-up growth in infants with cyanotic congenital heart disease (CHD).
METHODS:A total of 100 infants with cyanotic CHD who underwent surgical operation from January to December, 2017, were randomly divided into a high-calorie group (receiving calorie-enriched formula after surgery) and a conventional group (receiving standard formula after surgery), with 50 infants in each group. All infants were followed up for 6 months. The observation indices included body height, body weight, prealbumin, and N-terminal pro-brain natriuretic peptide before surgery, at the time of ventilator weaning and extubation after surgery, and at 1, 3, and 6 months after surgery. Height-for-age Z-score (HAZ), weight-for-age Z-score (WAZ), and weight-for-height Z-score (WHZ) were also assessed. Adverse reactions were recorded for both groups.
RESULTS:There were 25 cases (50%) and 21 cases (42%) of malnutrition in the high-calorie group and the conventional group respectively before surgery (
CONCLUSIONS:Compared with the standard formula, calorie-enriched formula can better help with postoperative catch-up growth in infants with cyanotic CHD.
