Analysis of animal models of chronic atrophic gastritis based on characteristics of clinical symptoms of traditional Chinese and Western medicine.
10.19540/j.cnki.cjcmm.20201123.601
- Author:
Tian-Tian LIU
1
;
Ya-Gang SONG
1
;
Shuo TIAN
1
;
Ming-San MIAO
1
Author Information
1. College of Pharmacy,Henan University of Chinese Medicine Zhengzhou 450046,China.
- Publication Type:Journal Article
- Keywords:
Chinese and Western medicine;
animal model;
chronic atrophic gastritis;
clinical symptoms
- MeSH:
Animals;
China;
Drugs, Chinese Herbal;
Gastritis, Atrophic;
Humans;
Medicine;
Medicine, Chinese Traditional;
Models, Animal
- From:
China Journal of Chinese Materia Medica
2021;46(4):777-781
- CountryChina
- Language:Chinese
-
Abstract:
Based on the clinical characteristics of chronic atrophic gastritis in traditional Chinese and Western medicine, the domestic and foreign relevant literature reports and animal models of chronic atrophic as well as the clinical diagnostic indicators of traditional Chinese and western medicine, chronic atrophic gastritis evaluation standard was summarized to evaluate and analyze the coincidence degree of clinical symptoms of the existing chronic atrophic gastritis animal models. The statistical results found that modeling methods with a higher coincidence degree with the existing chronic atrophic gastritis animal models are disease and syndrome combination mode-ling, surgical modeling, multifactor comprehensive modeling and MNNG modeling. Although the animal models were reproduced by such methods as etiology, pathogenesis and disease and syndrome combination similar to those of human beings, there is still a big gap with the natural disease state. Further in-depth studies and improvement shall be made in clinical practice in the hope to provide refe-rence for clinical practice and experimental studies of chronic atrophic gastritis.
