Inflammatory granuloma caused by injectable soft tissue filler (Artecoll).
10.5125/jkaoms.2013.39.4.193
- Author:
Sang Chang LEE
1
;
Jong Bae KIM
;
Byung Rho CHIN
;
Jin Wook KIM
;
Tae Geon KWON
Author Information
1. Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, Korea. kwondk@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Dermal filler;
Artecoll;
Inflammation;
Granuloma
- MeSH:
Biopsy;
Collagen;
Cosmetics;
Drainage;
Erythema;
Female;
Granuloma;
Hot Temperature;
Humans;
Inflammation;
Lip;
Nasolabial Fold;
Polymethyl Methacrylate
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2013;39(4):193-196
- CountryRepublic of Korea
- Language:English
-
Abstract:
Artecoll (Artes Medical Inc., San Diego, CA, USA) has recently been developed as a permanent synthetic cosmetic filler. We experienced an inflammatory granuloma resulting from a previous injection of Artecoll at the upper lip, which was regarded as a rare side effect of this filler. A 50-year-old female patient complained of swelling, dull pain, and heat in the right upper nasolabial fold area, which had started one week before her visit to Kyungpook National University Hospital. The patient received topical steroid therapy at a local clinic, which was not effective. At the injection site, a hard nodule was palpated and erythema was observed with mild tenderness. Antibiotic treatment and subsequent incision and drainage did not result in complete cure of the facial swelling, and the facial swelling and pain persisted. Computed tomography showed a lesion approximately 1-cm in size without clear boundaries and relatively increased nodular thickening. Finally, a subdermal lesion was removed via an intraoral vestibular approach. The lesion was diagnosed as inflammatory granuloma by a permanent biopsy. The patient had healed at two months after the filler injection. Although the soft tissue filler is widely used for cosmetic purposes, there is potential for complication, such as the inflammatory granuloma should be considered before treatment.
