Research Progress of Yiqi Huoxue Prescription in Treatment of Diabetic Angiopathy
10.13422/j.cnki.syfjx.20200705
- VernacularTitle:益气活血方治疗糖尿病血管病变的研究进展
- Author:
Yan-hong HU
1
;
Jing YANG
1
;
Cheng-kui XIU
1
;
Xue WANG
1
;
Jing-yi FANG
2
;
Jia-li WANG
1
;
Yi-qing LIU
1
;
Yi-nan LIU
1
;
Yan LEI
1
Author Information
1. China Academy of Traditional Chinese Medicine (TCM) Medical Experimental Center, Beijing Key Laboratory of Basic Research on Prevention and Treatment of Major Diseases by TCM, Beijing 100700, China
2. Chinese Medicine Research Institute of Guangdong Pharmaceutical University, Guangdong Research Center for Integrative Medicine in Metabolic Diseases, Guangzhou 510006, China
- Publication Type:Research Article
- Keywords:
Yiqi Huoxue prescription;
diabetic angiopathy;
Danggui Buxue decoction;
Danqi Jiangtang capsule;
Yiqi Huoxue Tongluo decoction;
Qi deficiency and blood stasis
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(8):1-12
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia. Its main complications of diabetes, such as diabetic angiopathy, have seriously affected the quality of life for patients, and have become an important cause of death and disability. The underlying pathological changes include macrovascular lesions and microvascular lesions. Diabetic macrovascular lesions mainly involve thoracic aorta, coronary artery, carotid artery, cerebral artery and peripheral blood vessels, etc., and the common clinical diseases include coronary heart disease, stroke, peripheral neuropathy, lower extremity arteriosclerosis, etc. Diabetic microvascular lesions mainly involve the heart, brain, kidney and other microvessels. Nowadays, various new oral hypoglycemic agents and insulin have emerged in the society and are widely used in clinical practice. However, traditional Chinese medicines(TCMs) have stable curative effect, less side effect, and can improve glucose metabolism, lipid metabolism, insulin resistance, oxidative stress, expression of inflammatory cytokines, vascular endothelial injury, microcirculation disorders, balance of fibrinolysis system and blood coagulation system, and improve the syndromes of TCMs, etc. They have been widely recognized and applied in the prevention and treatment of diabetic angiopathy. A profound understanding on the etiology, pathogenesis and treatment of diabetic angiopathy has been formed in Chinese medicine. Therefore, in this paper, we would summarizes the understanding on Chinese medicine for diabetic angiopathy and the mechanism of Yiqi Huoxue prescription in the treatment of diabetic angiopathy in the past three years.
