UPLC-Q-TOF-MS Analysis of Chemical Constituents of Paederiae Herba for Folk Use
10.13422/j.cnki.syfjx.20201812
- VernacularTitle:药用鸡矢藤药材化学成分的UPLC-Q-TOF-MS分析
- Author:
Tian-yuan GAO
1
;
Yu-tian LEI
1
;
Guo-lin TANG
1
;
Yan LIAN
1
;
Ling MA
2
;
Gui-hua JIANG
3
Author Information
1. School of Pharmacy，Chengdu University of Traditional Chinese Medicine（TCM），Chengdu 611137，China
2. School of Pharmacy，Chongqing Three Gorges Medical College，Chongqing 404120，China
3. School of Ethnic Medicine，Chengdu University of TCM，Chengdu 611137，China
- Publication Type:Research Article
- Keywords:
Paederia scandens;
P. scandens var. tomentosa;
P. stenophylla;
P. foetida;
chemical constituents;
UPLC-Q-TOF-MS
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(17):134-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The chemical constituents of ethanol extracts from Paederia scandens，P. scandens var.tomentosa，P. stenophylla and P. foetida used in folk were identified. And the differences of chemical constituents among the four kinds of ethanol extracts were compared. Method:The chemical constituents of four species of Paederia were qualitatively and rapidly analyzed by UPLC-Q-TOF-MS. The data were analyzed manually and matched through databases to determine the differences among the chemical constituents of four species of Paederia. Result:Twenty-three compounds were identified from four species, including 12 iridoid glycosides，such as paederoside，paederosidic acid，asperuloside，asperulosidic acid，paederosidic acid methyl ester and monotropein.5 quinic acid derivatives, such as 1-O-caffeoylquinic acid，chlorogenic acid，cryptochlorogenic acid,and 5 flavonoid glycosides，such as quercetin-3-O-rutinoside-7-O-glucoside,quercetin-3-O-rutinoside-7-O-xyloside，rutin and simple compoundkinsenoside. Conclusion:Based on the UPLC-Q-TOF-MS analysis of the chemical components of four kinds of Paederia，the four peaks with the highest response intensity were paederoside，paederosidic acid，asperuloside and asperulosidic acid，all of which were iridoid glycosides.
