Application Progress of Texture Analyzer in Pharmaceutical Preparation Research
10.13422/j.cnki.syfjx.20201063
- VernacularTitle:质构仪在药物制剂研究中的应用进展
- Author:
Yao-yao LI
1
;
Kai-xuan ZHANG
2
;
Hao-shu XIONG
2
;
Shun-nan ZHANG
2
Author Information
1. China Pharmaceutical University，Nanjing 211198，China
2. National & Local United Engineering Laboratory for Traditional Chinese Medicine Advanced Manufacturing Technology，Tasly Pharmaceutical Group Co. Ltd.，Tianjin 300410，China
- Publication Type:Research Article
- Keywords:
texture analyzer;
test modes;
pharmaceutical preparations;
physical parameters;
formulation screening;
quality control;
traditional Chinese medicine decoction pieces
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2020;26(21):226-234
- CountryChina
- Language:Chinese
-
Abstract:
Texture analyzer is a multifunctional physical property analyzer. Through a variety of test modes such as compression， puncture， shearing and stretching， hardness， adhesion， elasticity， cohesiveness and other physical property parameters are characterized. The results are objective， sensitive， and accurate， which can provide theoretical basis and reference for interpretation of basic theoretical， optimization of prescription technology and quality control research of pharmaceutical preparations. Firstly， the principles， test modes， measurement indexes and measurement data analysis methods of texture analyzer were summarized in this paper. Secondly， the application progress of texture analyzer in solid preparations， semi-solid preparations， liquid preparations， traditional Chinese medicine decoction pieces and their intermediates was described in detail， and compared with the commonly used measurement methods of physical property indicators. Finally， the application prospects of texture analyzer and its research contents to be improved were reviewed， so as to facilitate the use of texture analyzer by pharmaceutical researchers to promote the development of related fields of pharmaceutics， and to provide new ideas and methods for the research and development of pharmaceutical preparations.
