Progress of DNA methylation and hydroxymethylation in breast cancer
10.3760/cma.j.issn.1006-9801.2020.02.014
- VernacularTitle:DNA甲基化与羟甲基化在乳腺癌中的研究进展
- Author:
Qingtao NI
1
;
Chi PAN
Author Information
1. 江苏省泰州市人民医院肿瘤科 225300
- From:
Cancer Research and Clinic
2020;32(2):130-133
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is one of the most common malignant tumors in women and the second leading cause of death in female cancer patients. In recent years, the incidence of breast cancer has been increasing in China year by year, and the age of breast cancer patients becomes younger and younger. The pathogenesis of breast cancer is complex and related to many factors, such as age, family history and genetic variation. With the development of epigenetics, DNA modification plays an important role in the occurrence and development of breast cancer. This article reviews the research of DNA methylation and hydroxymethylation in breast cancer.