Research progress of lateral flow immunochromatographic detection system
10.3760/cma.j.cn114452-20200303-00166
- VernacularTitle:侧流免疫层析检测系统的研究进展
- Author:
Xin KONG
1
;
Guangrong LI
;
Jinbo LIU
Author Information
1. 西南医科大学附属医院医学检验部，泸州 646000
- From:
Chinese Journal of Laboratory Medicine
2020;43(6):678-682
- CountryChina
- Language:Chinese
-
Abstract:
Lateral flow immunochromatography is a real-time detection technology based on chromatographic membranes and nano-markers. Because of its simplicity, fastness and low cost, it is widely used in many fields, such as biomedicine, pathogen detection and food safety. Traditional lateral-flow immunochromatography relies on the naked eye, that has lower sensitivity, and can only provide qualitative or semi-quantitative results. With the application of different types of markers and sensitive detection equipment, lateral flow immunochromatography has enabled the quantitative and multi-component detection of analytes. The purpose of this paper is to describe the latest research progress of lateral flow immunochromatographic detection systems in combination with nano-labels, chromatographic membranes and band detectors, with a view to providing a basis for the selection of markers, improvement of chromatography membrane materials and detection instruments.
