Knowledges casted to the 2019 novel coronavirus nucleic acid amplification test from pathogenesis of viral pneumonia
10.3760/cma.j.cn114452-20200210-00059
- VernacularTitle:病毒性肺炎发病机制对新型冠状病毒核酸检测的提示
- Author:
Xiuying ZHAO
1
Author Information
1. 清华大学附属北京清华长庚医院检验医学科 清华大学临床医学院，北京 102218
- From:
Chinese Journal of Laboratory Medicine
2020;43(4):379-382
- CountryChina
- Language:Chinese
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Abstract:
An outbreak of 2019 novel coronavirus(2019-nCoV), results in novel coronavirus disease that began in Wuhan, China, has spread rapidly with cases now confirmed in multiple countries. Nucleic acid amplification test (NAAT), represent by reverse-transcriptase polymerase chain reaction (RT-PCR) plays an important role in disease diagnosis and treatment evaluation. The test results by RT-PCR have attracted much attention recently. It would be much help to combine the knowledge about its pathogenesis to judge the test results. This review will focus on understanding the specific RT-PCR performance of the 2019-nCoV, with combined knowledge of epidemiology, pathogenesis, clinical characteristics and pre-analysis quality control from viral pneumonia.
