Neuroimaging in the diagnosis and differentiation of Alzheimer′s disease
10.3760/cma.j.cn113694-20191107-00692
- VernacularTitle:神经影像学在阿尔茨海默病诊断与鉴别中的作用
- Author:
Guoping PENG
1
;
Xiaoyan LIU
;
Benyan LUO
Author Information
1. 浙江大学医学院附属第一医院神经内科，杭州 310003
- From:
Chinese Journal of Neurology
2020;53(5):321-327
- CountryChina
- Language:Chinese
-
Abstract:
Neuroimaging is of great value in the diagnosis and differentiation of Alzheimer′s disease. Structural imaging, especially structural magnetic resonance, can show the characteristic changes of brain atrophy in patients with Alzheimer′s disease, and effectively identify lesions in the brain. Functional imaging, mainly the molecular imaging of positron emission tomography can achieve intracranial retention of tracer that binds to the β-amyloid, which is of great value for the pathophysiological diagnosis of Alzheimer′s disease. This article introduces the application value of structural and functional magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography and other imaging examinations in the diagnosis and differentiation of Alzheimer′s disease.
