A study on the clinicopathological features and prognosis of colorectal cancer patients

VernacularTitle:结直肠癌患者的临床病理特征及预后分析
Author: Junhui YU ¹ ; Lan JIN ; Hongwei YAO ; Jin WANG ; Zhongtao ZHANG ; Yingchi YANG
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1. 首都医科大学附属北京世纪坛医院腹膜肿瘤外科　100038；首都医科大学附属北京友谊医院普通外科分中心　国家消化系统疾病临床医学研究中心　100050
From: Chinese Journal of General Surgery 2020;35(4):273-276
CountryChina
Language:Chinese
Abstract: Objective:To investigate prognostic factor in colorectal cancer (CRC).Methods:The clinicopathologic characteristics and progression free survival (PFS) of 181 CRC patients treated from Mar 2015 to Dec 2017 was collected for analysis. Univariate and multivariate analysis were performed to screen for prognostic factors affecting prognosis.Results:Univariate analysis found that age(χ 2=12.192, P=0.002), AJCC staging(χ 2=17.038, P=0.001), surgical approach(χ 2=6.105, P=0.047), postoperative carcinoembryonic antigen ( χ 2=10.081, P=0.001 ) and perioperative adverse events (χ 2=6.736, P=0.009)were significantly associated with prognosis. Multivariate analysis found that AJCC staging(Wald =8.104, P=0.044) and perioperative adverse events(Wald=7.656, P=0.006) were independent risk factors for prognosis. Conclusions:AJCC staging and perioperative adverse events can be used as independent risk factors for predicting prognosis in CRC patients.