Approach to the Hashimoto thyroiditis patient with thyroid hormone autoantibodies
10.3760/cma.j.cn311282-20191220-00564
- VernacularTitle:桥本甲状腺炎伴甲状腺激素自身抗体的临诊应对
- Author:
Ling LI
1
;
Li ZANG
;
Zhaohui LYU
;
Yiming MU
Author Information
1. 中国人民解放军总医院第一医学中心内分泌科，北京 100853(现在首都医科大学石景山教学医院，北京市石景山医院内分泌科 100043)
- From:
Chinese Journal of Endocrinology and Metabolism
2020;36(5):421-424
- CountryChina
- Language:Chinese
-
Abstract:
To discuss the clinical features and treatment of a 27-year-old female patient with Hashimoto thyroiditis and thyroxine autoantibody(T 4Ab) positive complained of abnormal thyroid function. The patient had no special clinical manifestations. Multiple measurements of thyroid function showed that surum FT 4 and TT 4 were elevated, while FT 3 and TT 3 remained normal, TSH was mainly elevated(occasionally normal or slight inhibited). We considered the possibility of the existence of laboratoury errors based on the inconsistency between the laboratory examination and clinical features, and the presence of T 4Ab was effectively confirmed by radioimmunoassay after comparing the test results of different methods and immunoprecipitation method. THAAb is a relatively rare antibody, which often leads to clinical misdiagnosis or even mistreatment. Therefore, clinicians should pay great attention to it.
