Research progress of targeted drug use related to nanoparticles
10.3760/cma.j.issn.1008-6706.2020.19.029
- VernacularTitle:纳米粒与靶向用药研究进展
- Author:
Chengbo LI
1
;
Pei LIU
Author Information
1. 中国医科大学附属第一医院传染科，沈阳 110001
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(19):2427-2432
- CountryChina
- Language:Chinese
-
Abstract:
Nanoparticles refer to particles having a particle size between 1 and 100 nm.Nanomaterials also have many applications in medicine and bioengineering.They have some physical properties that can effectively guide drugs into specific tissues and specific sites.For a long time, clinicians have been plagued by adverse drug reactions.Most drugs cannot be concentrated in targeted sites(tissue, organs, cells, etc.) due to pharmacokinetics.Scientists have been seeking a way to enter through various channels.In vivo, a drug that is distributed at a targeted site.This article will review the characteristics of nanoparticles in targeted therapy, the characteristics of in vivo distribution and current relevant application prospects.
