Research progress on hypogonadism with Prader-Willi syndrome
10.3760/cma.j.issn.1673-4912.2020.10.013
- VernacularTitle:Prader-Willi综合征性腺发育不良的研究进展
- Author:
Min YANG
1
;
Ying XIN
Author Information
1. 中国医科大学附属盛京医院小儿内分泌遗传代谢科，沈阳 110004
- From:
Chinese Pediatric Emergency Medicine
2020;27(10):770-774
- CountryChina
- Language:Chinese
-
Abstract:
Prader-Willi syndrome (PWS) is a rare genetic condition affecting both males and females.Hypogonadism is an important and prominent feature of PWS patients.Hypogonadismis is believed to have both a central (hypothalamic) and primary etiology, and the latter is paid more attention.Guidelines for treatment of hypogonadism with PWS are not available and most of them were recommended based on other kinds of hypogonadism.Therefore, it remains a challenge in adolescent and adult with PWS.This study reviews the mechanism, characteristics and treatment progress of hypogonadism with PWS, aiming to improve the understanding and treatment of gonadal dysplasia of PWS.
