Clinical characteristics of respiratory failure caused by pulmonary infection in infants with bronchopulmonary dysplasia in neonatal stage
10.3760/cma.j.issn.1673-4912.2020.05.009
- VernacularTitle:支气管肺发育不良患儿婴儿期肺炎呼吸衰竭临床特点分析
- Author:
Xueshan ZHAO
1
;
Wei XU
Author Information
1. 中国医科大学附属盛京医院儿内科，沈阳 110004
- From:
Chinese Pediatric Emergency Medicine
2020;27(5):358-361
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical features of respiratory failure caused by pulmonary infection in infants with bronchopulmonary dysplasia(BPD) in neonatal stage.Methods:We retrospectively collected the premature infants diagnosed with BPD in neonatal period(corrected for gestational age <12 months)from January 2013 to June 2017 in Shengjing Hospital of China Medical University.Respiratory failure occurred due to pulmonary infection.A total of 89 cases were divided into respiratory failure group and non-respiratory failure group according to whether respiratory failure occurred during the treatment period.The clinical characteristics of infants with BPD who suffered from respiratory infection were analyzed.Results:The median age of children with BPD was (5.60±2.90)months, 62 males(69.7%). Fifty-four cases were in respiratory failure group and 35 cases in non-respiratory failure group.The median age of admission[(5.16±2.47)months], average body weight[(4.91±1.75)kg] in respiratory failure group were significantly lower than those in non-respiratory failure group[(6.38±3.47)months, (6.16±2.53)kg, P<0.05]. Children with moderate to severe BPD were more likely to suffer from respiratory failure when developing lung infection in infancy ( P< 0.05). The incidence of neonatal respiratory distress syndrome in respiratory failure group(36 cases, 66.7%)was higher than that in non- respiratory failure group(14 cases, 40.4%)( P<0.05). Conclusion:The younger the age and the lower the weight of the infants with BPD, the more likely they are to develop respiratory failure when they suffer from lung infection in infancy.Those with moderate to severe BPD and with respiratory distress are more likely to develop respiratory failure when they have lung infection in infancy.
