Application of metagenomics in the respiratory infection diseases in children
10.3760/cma.j.cn101070-20200413-00629
- VernacularTitle:宏基因组测序在儿童呼吸道感染性疾病研究中的应用
- Author:
Fang XU
1
;
Adong SHEN
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院，北京市儿科研究所，儿科学国家重点学科，国家呼吸系统疾病临床医学研究中心，儿科重大疾病研究教育部重点实验室，儿童呼吸道感染性疾病研究北京市重点实验室，北京 100045
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(10):783-786
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory infectious diseases are a serious threat to children health.The early identification of the pathogen will lay the foundation for the diagnosis and treatment of the diseases.Metagenomics is a technique which directly sequences clinical samples without culture and reveals the information about all microbial sequences.It plays a very important part in the detection of pathogenic microorganisms, microbiology and interaction between microorganisms and host genes for the study of pathogenic organisms in children′s respiratory infectious diseases.In this article, the sequencing processes of metagenomics, its application in children′s respiratory infectious diseases and research progress at home and abroad were reviewed.
