Evolution of antibiotic resistance of Streptococcus pneumoniae in children
10.3760/cma.j.cn101070-20191016-00997
- VernacularTitle:儿童肺炎链球菌耐药性变迁
- Author:
Wei SHI
1
;
Wei GAO
;
Kaihu YAO
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院，国家呼吸系统疾病临床医学研究中心，北京市儿科研究所，儿科学国家重点学科教育部儿科重大疾病研究重点实验室，儿童呼吸道感染性疾病研究北京市重点实验室，北京 100045
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(7):521-525
- CountryChina
- Language:Chinese
-
Abstract:
Streptococcus pneumoniae is the dominant pathogen of respiratory tract infections in children.Due to the long-term overuse of antibiotics, the growing resistance of Streptococcus pneumoniae against many kinds of antimicrobial agents, including the β-lactamides, the macrolides, the fluoroquinolones and so on, increasing infections caused by drug-resistant pneumococcal isolates, as well as the wide prevalence of such infections have posed great challenges to the selection of antibiotics in clinical practice.In this article, changes of resistance patterns of Streptococcus pneumoniae isolates against commonly used antimicrobial agents in Chinese children in the past 30 years were reviewed.The rapid development of antibiotic resistance of Streptococcus pneumoniae necessitates the prevention and control of Streptococcus pneumoniae infections as well as the reduction of unreasonable use of antibiotics.
