Etiologic characteristics of adults with community-acquired pneumonia
10.3760/cma.j.issn.1671-0282.2020.09.013
- VernacularTitle:成人社区获得性肺炎病原学特点分析
- Author:
Jing CHEN
1
;
Xiaoguang LI
;
Wei WANG
;
Fei LIN
;
Ying JIA
;
Jie XU
Author Information
1. 北京大学第三医院感染疾病科 100191
- From:
Chinese Journal of Emergency Medicine
2020;29(9):1210-1213
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the etiologic characteristics of adults with community acquired pneumonia (CAP).Methods:Respiratory tract specimens were collected from 246 cases of community acquired pneumonia in Peking University Third Hospital after excluding tuberculosis, pulmonary tumor, non-infectious pulmonary interstitial disease, pulmonary edema, pulmonary atelectasis, pulmonary embolism, pulmonary eosinophil infiltration and pulmonary vasculitis. Nineteen respiratory pathogens were tested by multiple real-time fluorescent quantitative PCR to investigate the distribution of respiratory pathogens.Results:The positive rate of nucleic acid detection in respiratory pathogens was 46.7%, among which 25.6% was virus, 19.9% atypical pathogens and 18.7% bacteria. The most prevalent viruses were influenza virus (14.6%), parainfluenza virus (2.8%) and rhinovirus (2.8%). The three most prevalent bacteria were Streptococcus pneumoniae (8.5%), Haemophilus influenzae (6.1%)and Klebsiella pneumoniae (2.4%). The positive rate of Mycoplasma pneumoniae was higher in patients <65 years than that in patients≥65 years (21.3% vs 2.6%, χ 2=10.376, P=0.001). Conclusions:Respiratory virus is the leading respiratory pathogens in community acquired pneumonia exceeding bacteria and Mycoplasma pneumoniae, Influenza virus and Streptococcus pneumoniae are the top three pathogens in CAP.
