Research progress in drug treatment of chronic obstructive pulmonary disease with pulmonary hypertension
10.3760/cma.j.cn121382-20200226-00415
- VernacularTitle:慢性阻塞性肺疾病合并肺动脉高压的药物治疗进展
- Author:
Beibei GAO
1
;
Xiaofang LI
;
Yimin MAO
Author Information
1. 河南科技大学临床医学院,河南科技大学第一附属医院,洛阳 471003
- From:
International Journal of Biomedical Engineering
2020;43(4):335-339
- CountryChina
- Language:Chinese
-
Abstract:
Chronic obstructive pulmonary disease (COPD) is well known as a chronic lung disease. In recent years, with the deepening of its understanding, various complications of COPD, especially pulmonary hypertension(PH) have received more and more attention. COPD patients with PH have an increased fatality rate and a poor prognosis, which seriously affects the quality of life of the patients, and the treatment of the disease lacks effective drugs. In order to fully understand the current status of the treatment of the disease, the research progress of the drug treatment of COPD combined with PH was reviewed. The results show that for patients with COPD and PH, the best treatment should be given to their underlying diseases. The use of statins and fasudil may be beneficial, but the effect of targeted drugs is still controversial. In the future, more large randomized controlled trials need to be carried out to further clarify the efficacy of various drugs on COPD.