Progress in the pathogenesis of neonatal necrotizing enterocolitis
10.3760/cma.j.issn.1673-4408.2020.02.010
- VernacularTitle:新生儿坏死性小肠结肠炎发病机制研究进展
- Author:
Fengning ZHANG
1
Author Information
1. 南京医科大学附属儿童医院新生儿医疗中心
- Keywords:
Neonatal necrotizing enterocolitis;
Pathogenesis
- From:
International Journal of Pediatrics
2020;47(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal necrotizing enterocolitis (NEC) is one of common gastrointestinal critical diseases in the neonatal medical center,with high morbidity and mortality.The pathophysiological mechanism of the NEC is still unclear so far.Thus,the treatment of NEC is currently mainly limited to the symptomatic treatment in clinic.In the recent years,the studies on the pathogenesis of NEC have been increasing.This artical clarified the pathogenesis of NEC in six aspects:the pathogeny of intestinal immune function,gut microbiome,oxidative stress reaction,breastfeeding,blood transfusion and inflammatory mediators,to provide a new detection in prevention,diagnosis and treatment of NEC.
