Risk factors for early recurrence of hepatocellular carcinoma after TACE
10.13929/j.issn.1672-8475.2020.02.001
- Author:
Lin DENG
1
Author Information
1. Clinical Medical College, Ningxia Medical University
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Chemoembolization, therapeutic;
Recurrence
- From:
Chinese Journal of Interventional Imaging and Therapy
2020;17(2):65-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the risk factors of early recurrence of hepatocellular carcinoma (HCC) after TACE. Methods Totally 42 advanced HCC patients who underwent TACE were followed up for 6 months, and the clinical data and imaging data were compared and analyzed between early relapse and non-relapse patients. Results During 6 months' follow-up, early recurrence of HCC was detected in 23 patients (recurrence group), while no recurrence was found in 19 patients (no recurrence group). The ratio of Albumin>35 g/L patients was lower, of AFP >400 ng/ml patients was higher in recurrence group than in no recurrence group (both P<0.05), while the level of alanine transaminases (ALT) was higher in recurrence group (P<0.05), whereas tumor differentiation were higher in no recurrence group than in recurrence group (P<0.05). The number of tumor foci and maximum diameter of HCC were relatively higher, while ADC value and ratio of complete envelope were lower in recurrence group (all P<0.05). Multivariate Logistic regression analysis showed that the radio of AFP>400 ng/ml (OR=3.313, P=0.041), tumor differentiation (OR=1.463, P=0.038), tumor number (OR=2.216, P=0.028) and ADC value (OR=0.025, P=0.003) were independent risk factors for early recurrence of HCC after TACE. Conclusion: Early recurrence of HCC after TACE was independently related to AFP, pathological differentiation, the number of tumor foci and ADC values.
