Advances in Research on MicroRNA-7 in Colorectal Cancer
10.3969/j.issn.1008-7125.2019.07.014
- Author:
Xiaohong ZHANG
1
Author Information
1. Department of Gastroenterology, First Affiliated Hospital of Kunming Medical University
- Publication Type:Journal Article
- Keywords:
Colorectal Neoplasms;
Diagnosis;
MicroRNAs;
Therapy
- From:
Chinese Journal of Gastroenterology
2019;24(7):444-446
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a class of small endogenous non-coding RNAs which are closely related to the development and progress of colorectal cancer. Most studies show that expression of miR-7 is decreased in colorectal cancer tissues and cell lines, and negatively regulates the expressions of PAX6, YY1, etc., thereby participating in the development, proliferation, invasion and metastasis of colorectal cancer. MiR-7 is expected to become a new target for the diagnosis, treatment, and prognosis of colorectal cancer. This article reviewed the research progress of miR-7 in colorectal cancer.
