Advances in Research on Role and Mechanism of Polyphylla Saponin in Digestive System Tumors
10.3969/j.issn.1008-7125.2019.09.012
- Author:
Yang LI
1
Author Information
1. Gastroenterology Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine(Jiangsu Province Hospital of Chinese Medicine)
- Publication Type:Journal Article
- Keywords:
Digestive System Neoplasms;
Mechanisms;
PARIS Polyphylla;
Polyphylla Saponin
- From:
Chinese Journal of Gastroenterology
2019;24(9):573-576
- CountryChina
- Language:Chinese
-
Abstract:
Polyphylla saponin is the major effective ingredient of polyphylla. Pharmacology research showed that polyphylla saponin could effectively inhibit the occurrence and development of malignant tumor of digestive system via inhibiting tumor cell proliferation, promoting tumor cell apoptosis, inhibiting tumor neovascularization, inhibiting tumor cell migration, regulating tumor cell immune function, regulating tumor cell resistance to chemotherapeutic drugs. This article reviewed the role and mechanism of polyphylla saponin in digestive system tumors.
