Study on Colon Capsule Endoscopy in Diagnosing Colorectal Polyps
10.3969/j.issn.1008-7125.2020.05.004
- VernacularTitle: 结肠胶囊内镜诊断结直肠息肉的研究
- Author:
Huan LIU
1
Author Information
1. Department of Gastroenterology, The First Affiliated Hospital of Air Force Medical University (Xijing Hospital)
- Publication Type:Journal Article
- Keywords:
Colon Capsule Endoscopy;
Colonoscopy;
Colorectal Polyps;
Diagnosis
- From:
Chinese Journal of Gastroenterology
2020;25(5):271-275
- CountryChina
- Language:Chinese
-
Abstract:
Background: Colon capsule endoscopy (CCE) is an innovative, safe and noninvasive endoscopic technique for the diagnosis of colorectal diseases without the need of sedation. Aims: To evaluate the accuracy and safety of the second generation CCE in diagnosing colorectal polyps. Methods: In a prospective study, 32 patients who were diagnosed as having colorectal polyps (defined as at least one polyp of 6 mm or larger in diameter; or three or more polyps of any size) by colonoscopy from Jan. 2014 to Sep. 2015 at the Xijing Hospital were enrolled. Colonoscopic polypectomy was performed on the second day of CCE. Taking the finding of therapeutic colonoscopy as gold standard, the sensitivity of CCE in diagnosing colorectal polyps was evaluated. Furthermore, the colonic cleansing, the transit time and excretion rate of the capsule, as well as the CCE-related adverse events were assessed. Results: In one patient, no polyp was found under the therapeutic colonoscopy. CCE detected the polyps in 27 of 31 patients, the per-patient sensitivity was 87% (95% CI: 69%-96%). The sensitivity of CCE in detecting polyps ≥10 mm, ≥6 mm and ≤5 mm in diameter were 82% (95% CI: 48%-97%), 76% (95% CI: 54%-90%), and 66% (95% CI: 53%-77%), respectively. The overall cleanliness was adequate in 71% (95% CI: 51%-87%) of the patients. The mean gastrointestinal transit time of the capsule was (11.42±5.23) hours, and the mean colonic transit time was (7.47±4.75) hours. The capsule excretion rate within the battery life was 75%. There were no adverse events related to CCE. Conclusions: The second generation CCE is safe and has a potential value in diagnosing colorectal polyps. The sensitivity in detecting polyps of 10 mm and 6 mm or larger in diameter is fairly well.
