CT serosa high enhancement sign in differentiating T3 from T4a gastric cancer
10.13929/j.1003-3289.201903119
- Author:
Mengmei ZHANG
1
Author Information
1. Department of Imaging, The First Affiliated Hospital of Kunming Medical University
- Publication Type:Journal Article
- Keywords:
Gastric neoplasms;
Serosa high enhancement sign;
Serosa invasion;
Tomography;
X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2019;35(9):1361-1364
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of serosa high enhancement sign in differentiating T3 and T4a gastric cancer. Methods: Abdominal three-phase enhanced CT images of 104 patients with stage T3 or T4a gastric cancer confirmed by operation and pathology were analyzed retrospectively. The occurrence rate of serosa high enhancement sign in each stage was observed and compared. Using serosa high enhancement sign as the criterion for diagnosis of T4a stage gastric cancer,its accuracy, sensitivity, specificity, positive predictive value and negative predictive value were calculated. Results: Among 104 patients, 34 were found with T3 stage and 70 were T4a stage gastric cancer. The accuracy, sensitivity, specificity, positive predictive value and negative predictive value of serosa high enhancement sign in diagnosis of stage T4a gastric cancer was 77.88% (81/104), 81.43% (57/70), 70.59% (24/34), 85.07% (57/67) and 64.86% (24/37), respectively. The occurrence rate of serosa high enhancement sign in arterial phase, venous phase and delayed phase of T4a gastric cancer was 32.86% (23/70), 75.71% (53/70) and 62.86% (44/70), respectively. There was significant difference of occurrence rates between arterial phase and venous phase (P<0.001), also between arterial phase and delayed phase (P=0.001), but no significant difference was found between venous phase and delayed phase CT images (P=0.143). Conclusion: Serosa high enhancement sign on enhance CT has relatively high accuracy, sensitivity and specificity for diagnosis of T4a gastric cancer, which can be used to judge the serosa invasion of gastric cancer. It is recommended to observe this sign in venous or delayed phase.
