Research progresses of arterial spin labeling imaging in mild cognitive impairment
10.13929/j.issn.1003-3289.2020.07.039
- VernacularTitle: 动脉自旋标记成像用于轻度认知障碍研究进展
- Author:
Mingjuan QIU
1
Author Information
1. Department of Medical Imaging, East Hospital Affiliated to Tongji University
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Mild cognitive impairment;
Regional cerebral blood flow
- From:
Chinese Journal of Medical Imaging Technology
2020;36(7):1093-1096
- CountryChina
- Language:Chinese
-
Abstract:
Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD), the pathogenesis of AD is still unclear. Cerebral blood flow is an important indicator of brain function. Various causes lead to decreased regional cerebral blood flow (rCBF) and damage brain. Arterial spin labeling (ASL) MRI is an imaging technology that measure rCBF by magnetizing hydrogen protons in labeled arterial blood as endogenous tracers. The progresses of ASL imaging in early diagnosis and monitoring progression as well as evaluation on therapeutic effects of MCI were reviewed in this article.