Differential diagnosis of ≤5 cm gastric stromal tumor and gastric schwannoma with whole tumor volume histogram analysis based on enhanced CT
10.13929/j.issn.1003-3289.2020.08.022
- VernacularTitle: 基于增强CT全瘤直方图分析鉴别诊断≤5 cm胃肠道间质瘤与胃神经鞘瘤
- Author:
Jun SUN
1
Author Information
1. Department of Medical Imaging, Northern Jiangsu People's Hospital
- Publication Type:Journal Article
- Keywords:
Diagnosis, differential;
Histogram;
Stomach neoplasms;
Tomography, X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2020;36(8):1211-1214
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the value of whole tumor volume histogram analysis based enhanced CT in differential diagnosis of ≤5 cm gastrointestinal stromal tumor (GIST) and gastric schwannoma (GS). Methods: Totally 51 patients with pathologically proven ≤5 cm GIST and 16 with GS underwent abdominal enhanced CT, and the images were retrospectively analyzed. ROIs were chosen at dual-phase CT images of total tumor, and histogram analysis was performed using MaZda software to obtain the mean, variation, skewness, kurtosis and percentiles (Perc.1%, Perc.10%, Perc.50%, Perc.90%, Perc.99%). The differences of the above parameters were compared between 2 groups, and their diagnostic efficacies were analyzed. Results: Among histogram parameters of arterial phase images, the mean, variation and percentiles (Perc.1%, Perc.10%, Perc.50%, Perc.90%) values of GIST group were 125.71±13.57, 145.31 (110.44,191.84), 97.63±16.40, 110.45±14.69, 125.67±13.46 and 141.06±13.48, respectively, while of GS group were 139.97±19.08, 99.21 (80.97, 135.21), 113.38±19.86, 127.44±18.90, 140.25±19.20 and 152.75±20.00, respectively. There were statistical differences between 2 groups (all P<0.05), and the AUC of ROC values were 0.76, 0.72, 0.75, 0.78, 0.76 and 0.73,respectively. Among histogram parameters of venous phase images, the variation value of GIST group was 144.08 (106.58, 221.25), and of GS was 94.38 (80.97,122.90, P<0.05), and the AUC was 0.78. Conclusion: Histogram analysis based enhanced CT is valuable for differentiating ≤5 cm GIST and GS, while Perc.10% (on arterial phase) and variation (on venous phase) have relative high diagnostic efficacy.
