Clinical features and imaging findings of adrenocortical carcinoma in children
10.13929/j.issn.1003-3289.2020.10.013
- VernacularTitle: 儿童肾上腺皮质癌临床及影像学表现
- Author:
Li HUANG
1
Author Information
1. Department of Radiology, Guangzhou Women and Children's Medical Center
- Publication Type:Journal Article
- Keywords:
Adrenocortical carcinoma;
Child;
Magnetic resonance imaging;
Tomography, X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2020;36(10):1495-1498
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe clinical features and imaging findings of children adrenocortical carcinoma (ACC). Methods: Clinical and imaging data of 13 children with ACC confirmed by pathology were retrospectively analyzed. Among them, 11 cases received preoperative abdominal CT and 4 cases received preoperative abdominal MR scanning. The clinical and imaging manifestations of ACC were observed. Results: Among 13 ACC children, 10 (10/13, 76.92%) were female, and most common clinical manifestations included obvious masculinization (9/13, 69.23%), Cushing syndrome (4/13, 30.77%), clitoral hypertrophy (3/13, 23.08%), pubic hair presbyopia (3/13, 23.08%), abdominal pain and abdominal mass (2/13, 15.38%). Ten children (10/13, 76.92%) had elevated serum androgen. CT showed largeadrenal masses with maximum diameter>6 cm in 7 cases (7/13, 53.85%), the lesions were lobulated in 8 (8/13, 61.54%) cases. Among 13 lesions, 5 (5/11, 45.45%) had uneven density with calcification foci. All lesions unevenly and obviously enhanced after enhancement (11/11, 100%), and "network-like" changes were observed in 8 cases (8/11, 72.23%). Tumor involvement of surrounding tissue and renal vein or inferior vena cava tumor thrombi were noticed in 2 cases (2/11, 18.18%). MR T2WI showed slightly high signal lesions in 3 cases and medium signal lesion in 1 case, all uneven enhanced after enhancement. Conclusion: Imaging manifestations of children ACC had certain characteristics, combining with clinical manifestations were helpful to diagnosis of this disease.
