Correlation between contrast-enhanced ultrasound and 18F-FDG PET/CT for judging activity of Takayasu arteritis
10.13929/j.issn.1003-3289.2020.10.007
- VernacularTitle: 超声造影与18F-FDG PET/CT判断多发性大动脉炎活动性的相关性
- Author:
Yang CHEN
1
Author Information
1. Department of Ultrasound, Rhe First Affiliated Hospital of Zhengzhou University
- Publication Type:Journal Article
- Keywords:
Fluorodeoxyglucose F18;
Positron-emission tomography;
Takayasu arteritis;
Ultrasonography, interventional
- From:
Chinese Journal of Medical Imaging Technology
2020;36(10):1470-1474
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between contrast-enhanced ultrasound (CEUS) and 18F-FDG PET/CT for judging activity of Takayasu arteritis (TA). Methods: A total of 36 TA patients who underwent CEUS and 18F-FDG PET/CT were enrolled, the related laboratory indexes and imaging parameters were compared. The correlation between CEUS and 18F-FDG PET/CT for judging TA activity was analyzed. Results: There were significant differences of disease duration, Indian Takayasu arteritis clinical activity score (ITAS 2010), carotid occlusion ratio, CEUS peak intensity, PET/CT uptake and the maximal standardized uptake value (SUVmax) between CEUS significantly enhanced group and non-enhanced or little enhanced group (all P<0.05). CEUS was moderately correlated with PET/CT visual score (r=0.697, P<0.001) and slightly correlated with NIH criteria of clinical activity and SUVmax (r=0.385, P=0.018; r=0.477, P=0.014). Taken 18F-FDG PET/CT visual score as the criterion of TA activity, the sensitivity and specificity of NIH criteria of clinical activity was 0.783 and 0.769, of CEUS was 1.000 and 0.846, and AUC was 0.776 and 0.923, respectively. Conclusion: Significant positive correlation existed between CEUS and 18F-FDG PET/CT for judging TA activity. Taken18F-FDG PET/CT visual scoring as the standard, CEUS had higher sensitivity and specificity than clinical disease activity criteria, and might be used as an effective method for judging TA activity.
